Spider-Man 3
A symbiote from a meteorite bonds with Peter's costume and makes him aggressive, straining his bond with Mary Jane. He faces Harry Osborn as the New Goblin, the Sandman, and Eddie Brock, who becomes Venom. Harry sacrifices himself to save Peter, and the symbiote is destroyed.
Worlds visited
Characters
Spider-Man (Peter Parker), Mary Jane Watson, Harry Osborn, Venom, Sandman, May Parker, J. Jonah Jameson, The Lizard, Gwen Stacy, George Stacy, Norman Osborn (Green Goblin), Uncle Ben, Flash Thompson